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Image Search Results
Journal: Experimental and Therapeutic Medicine
Article Title: Assessing biological aging following systemic administration of bFGF-supplemented adipose-derived stem cells with high efficacy in an experimental rat model
doi: 10.3892/etm.2019.7251
Figure Lengend Snippet: The schematic schedule of the present experimental protocol. The isolated fat tissues were washed and digested. A total of 10 6 ADSCs (P2) were administered via the femoral vein. At fat harvest, ADSC injection, and 1,3, and 5 weeks later, blood and urine samples were analyzed. ADSC, adipose-derived stem cells; bFGF, basic fibroblast growth factor.
Article Snippet:
Techniques: Isolation, Injection, Derivative Assay
Journal: Experimental and Therapeutic Medicine
Article Title: Assessing biological aging following systemic administration of bFGF-supplemented adipose-derived stem cells with high efficacy in an experimental rat model
doi: 10.3892/etm.2019.7251
Figure Lengend Snippet: Doubling time of ADSCs cultured with or without bFGF. bFGF markedly increased the cell doubling rate at P1 and P2. Doubling time was markedly shorter in the bFGF treated group, thus indicating the progenitor cell feature. Data are presented as the mean ± standard error of the mean. *P<0.0001. ADSC; adipose-derived stem cells; bFGF, basic fibroblast growth factor; P1, passage 1; P2, passage 2.
Article Snippet:
Techniques: Cell Culture, Derivative Assay
Journal: Experimental and Therapeutic Medicine
Article Title: Assessing biological aging following systemic administration of bFGF-supplemented adipose-derived stem cells with high efficacy in an experimental rat model
doi: 10.3892/etm.2019.7251
Figure Lengend Snippet: The liver signal can be regulated by administration of ADSCs cultured with bFGF supplementation. (A) ALT and (B) α-amylase levels in bFGF supplemented (right) and non-supplemented (left) groups. ALT level was downregulated in the bFGF-supplemented ADSC administration group. Additionally, α-amylase level was unchanged in bFGF non-treated group, but it was lower in the bFGF-supplemented group. This suggested that ADSCs maintain liver metabolism in anti-aging systems. Data are presented as the mean ± standard error of the mean. ADSC; adipose-derived stem cells; bFGF, basic fibroblast growth factor; ALT, alanine transaminase.
Article Snippet:
Techniques: Cell Culture, Derivative Assay
Journal: Experimental and Therapeutic Medicine
Article Title: Assessing biological aging following systemic administration of bFGF-supplemented adipose-derived stem cells with high efficacy in an experimental rat model
doi: 10.3892/etm.2019.7251
Figure Lengend Snippet: The markers of kidney function changed following ADSC administration in the bFGF supplemented group. (A) Urine protein, (B) urine BUN, and (C) urine creatinine levels in bFGF supplemented (right) and non-supplemented (left) groups. Urine protein was markedly decreased in the bFGF-supplemented ADSC administration group compared with bFGF non-treated group. Urine BUN and creatinine levels exhibited similar patterns to that of urine protein. bFGF affects the biological markers associated with hepatic and renal functions. Data are presented as the mean ± standard error of the mean. ADSC; adipose-derived stem cells; bFGF, basic fibroblast growth factor; BUN, blood urea nitrogen.
Article Snippet:
Techniques: Derivative Assay